which is the correct order of the steps in a generalized signal transduction pathway?

Answers

Answer 1

the steps in the signal transduction pathway can vary depending on the specific signaling system involved, and some steps may occur simultaneously or in a different order.

Reception: The signal molecule (ligand) binds to a specific receptor protein on the cell membrane or inside the cell.

Transduction: The binding of the signal molecule to the receptor activates a series of intracellular signaling molecules, which amplify the signal and transmit it to the effector proteins.

Amplification: The signaling molecules activate a cascade of enzymatic reactions, resulting in the production of second messengers, such as cyclic AMP (cAMP) or inositol triphosphate (IP3), that amplify the signal.

Modulation: The second messengers or other signaling molecules modulate the activity of downstream effectors, such as ion channels or enzymes, leading to changes in the cell behavior of pathway.

Response: The changes in cell behavior can range from alterations in gene expression to changes in metabolism, cell growth, or movement, leading to a physiological response to the original signal.

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Related Questions

the global tuna trade is a huge money-making venture, due to the japanese peopleâs desire for sushi and sashimi. trace the lengthening tuna commodity chain to understand the interconnectedness of worldwide trade and commerce.
Years of overfishing send fish populations off Japan's coast into decline.
Japanese traders start buying fish caught in the North Atlantic.
Tuna caught in the North Atlantic is sold at the Tsukiji Fish Market in Tokyo.
North Atlantic fish is made into sushi for consumption in Japanese restaurants

Answers

1. Years of overfishing population have pushed Japan's coastal fish stocks into the abyss.

2. Japanese traders start buying North Atlantic fish.

3. Tuna caught in the North Atlantic are sold at Tsukiji Market in Tokyo.

4. North Atlantic fish are made into sushi for consumption in Japanese restaurants.

What is the population and its examples?

Population is generally defined as the group of people living in an area. Examples - US population, India population, China population, city general population, etc.

Why is it called population mean?

A population mean is an average computed over a group, distribution, or population. It is derived by dividing the sum of all population variables by the total number of variables in the population. where is μ population mean. ∑X is the sum of all observations in the population.  

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What does a single death is a tragedy a million deaths is a statistic mean?

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The quote "A single death is a tragedy; a million deaths is a statistic" is often attributed to Joseph Stalin, the former leader of the Soviet Union. It expresses the idea that people tend to be more emotionally affected by stories of individual suffering and loss than by statistics that represent large numbers of people.

The quote highlights a common psychological phenomenon called the "identifiable victim effect," which suggests that people are more likely to be moved to help or donate when they can identify a specific person or group that is suffering, rather than when presented with a more abstract, statistical representation of the problem.

While statistics can help us understand the scope and magnitude of a problem, they can also feel overwhelming and distant. Focusing on individual stories can help to personalize the issue and motivate people to take action.

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What are the types of unemployment?

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Seasonal unemployment, Frictional unemployment, Cyclical unemployment and Structural unemployment are the four types of unemployment .

The state of being able to work, actively looking for job, but unable to do so. It is crucial to remember that a person must be actively seeking payed employment in the labor force in order to be termed unemployed.

When someone is actively looking for work and is considered to be employable, they are said to be unemployed. Those without work are more likely than those with jobs to experience sadness, anxiety, and other mental health problems. According to studies, those who have been unemployed for longer stretches of time than those who have consistently held down a job are in worse health by the age of 50.

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what is the purpose of no fear shakespeare romeo and juliet ?

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The purpose of No Fear Shakespeare: Romeo and Juliet is to make the language of Shakespeare's play more accessible to modern audiences.

Shakespeare's plays were written in Early Modern English, which can be difficult for contemporary readers to understand. No Fear Shakespeare provides a side-by-side translation of the original text and a modern English version, allowing readers to easily comprehend the story and themes of Romeo and Juliet.

This makes it easier for students to study and analyze the play, and for general audiences to enjoy it. No Fear Shakespeare is an excellent resource for anyone looking to better understand the language and themes of Shakespeare's works.

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who also won the lucasian professor of mathematics position?

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Since its establishment, the professorship has been held by, among others, Isaac Newton, Charles Babbage, George Stokes, Joseph Larmor, Paul Dirac, and Stephen Hawking.

The Lucasian Professor is the title held by the Lucasian Chair of Mathematics , a chair in mathematics at the University of Cambridge in England. Henry Lucas, a member of parliament from Cambridge University in 1639–1640, established the post in 1663, and King Charles II formally established it on January 18, 1664. One of the most esteemed academic positions in the entire globe, according to The Daily Telegraph. The chair has been held by a number of notable individuals over the years, including Isaac Newton, Charles Babbage, George Stokes, Joseph Larmor, Paul Dirac, and Stephen Hawking.

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what is the background to the richard ramirez incident in 2012

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In 2012, Richard Ramirez, an American serial killer died of natural causes in California State Prison.

He was convicted of 13 counts of murder, five counts of attempted murder, 11 counts of assault, and 14 counts of burglary from 1984 to 1985 in the USA.


The Richard Ramirez incident in 2012 is actually a case of mistaken identity. Richard Ramirez, also known as the "Night Stalker," was a convicted serial killer who committed his crimes in the 1980s in the USA. However, in 2012, a man named Richard Ramirez Jr. was arrested in Houston, Texas for the murder of his mother.

Due to their shared name, many people initially believed that the "Night Stalker" had committed another crime, but it was quickly clarified that the two men were not the same person. The Richard Ramirez Jr. incident in 2012 was unrelated to the crimes committed by the "Night Stalker" in the 1980s.

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Capital can be differentiated between physical capital and human capital.Human capital isA. the knowledge and skills workers acquire from education and training or from their life experiences.B. the new developments in machinery and software.C. the energy use to bring together the factors of production to produce goods and services.D. the goods manufactured to produce other goods and services.

Answers

A. The information and skills that employees pick up through their schooling, training, or life experiences.

Difference between Human and Physical capital.

The ability to produce goods and services is referred to as human capital, which is the knowledge, skills, and talents that people have earned via school, training, and life experiences. It includes the collection of skills, routines, social traits, and personality traits, such as inventiveness, that are expressed in the capacity to do work in a way that generates economic value. On the other hand, physical capital describes the stock of constructed production tools such as structures, tools, and machinery, that are employed in the creation of commodities and services. The terms energy and natural resources employed in production are frequently used to describe physical capital.

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If a null hypothesis is rejected, what is the conclusion about the treatment?A) the treatment most likely has an effectB) the treatment is proven to be effectiveC) used the wrong treatment in the experimentD) rejecting the null suggests nothing about the treatment

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If a null hypothesis is rejected, it means that there is evidence that the treatment has an effect and the probability of the observed results occurring by chance is low.

The correct option is A)

However, rejecting the null hypothesis does not necessarily mean that the treatment is effective or that it has a significant effect.

The conclusion that can be drawn from rejecting the null hypothesis is that there is evidence that the treatment has an effect, but the magnitude and direction of the effect are still uncertain. Further analysis is needed to determine the precise nature of the effect, as well as its practical significance.

It is also important to note that rejecting the null hypothesis does not necessarily mean that the treatment is the best or only option available. It is possible that other treatments or interventions may be more effective, or that the observed effect of the treatment may not be large enough to be clinically or practically significant.

In conclusion, rejecting the null hypothesis is an important step in analyzing experimental data, but it is only the beginning of the process. More detailed analysis and interpretation are necessary to fully understand the implications of the results for the treatment being studied.

Thus, the correct option is A)

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How much do consumers spend on the Super Bowl?

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The National Retail Federation (NRF) estimates that consumers $16.5 billion, or $85.36 per person, will be spent on food, beverages, clothing, decorations, and other goods on the day.

The projected amount for this year represents an increase of $1.9 billion from the $14.6 billion figure for Bowl tickets in 2022. At addition to the 17.8 million individuals who intend to watch the game in a bar or restaurant, 103.5 million people this year intend to host or attend parties.

It is anticipated that $16.5 billion, or $85.36 per person, will be spent on all expenditures for the day, including food, drinks, clothing, decorations, and other items. The $82,000 that the players on the losing side will receive may help them feel a bit better, even though it doesn't lessen the pain of defeat.

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a pink pigeon was rescued from a nyc park. a wildlife group believes it was dyed for use in a ___

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A pink pigeon was rescued from a NYC park and a wildlife group believes it was dyed for use in a gender reveal party.

In a news article published in a leading newspaper reported that a pink plumaged pigeon was rescued from a New York City park. A wildlife group believed that it was probably dyed for use in a gender reveal party.  It was a king pigeon which was found wandering Madison Square Park in Manhattan and was taken into care.

The pigeon was dyed pink as pink is not a natural color for a pigeon. The natural colors and plumages for pigeons range from black to white, brown, blue, and gray. The domestic king pigeon was deliberately dyed this color and released probably as part of a gender reveal party (as pink is the color indicating that it is a girl).

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how did georgia contribute to the united statesâ effort in world war ii?

Answers

In terms of both military and industrial production, Georgia was a significant player in the American effort during World War II. Numerous military stations and camps, such as Fort Benning and Fort Gordon, were located in Georgia.

How can it be explained in detail?

This provided training for a large number of soldiers, including infantry, artillery, and armour divisions. In addition to servicing and repairing aircraft utilised in the war effort, the Warner Robins Air Logistics Center was essential.

Georgia established itself as a major hub for industry, producing items like ships, armaments, and aeroplanes. The Bell Aircraft Corporation in Marietta built a sizable quantity of B-29 Superfortress bombers, and a huge shipyard that built Liberty ships was located in the city of Savannah.

All in all, Georgia's military and industrial contributions to World War II were significant components of the US effort.

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who is blanche taylor moore?

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Blanche Kiser Taylor Moore (born February 17, 1933) is an American convicted murderer and possible serial killer from Alamance County, North Carolina.

why were coastal towns important to the development of globalization

Answers

Answer:

Indirect impacts of globalization include increased pollution, loss of habitat and biodiversity, and diminished quality of air, soil and water resources

Explanation:

Who was the 1st African American elected to the U.S. Senate in 1870?

Answers

The first African American elected to the U.S. Senate was Hiram Rhodes Revels of Mississippi. He was elected in February 1870.

what is the meaning of conflict theory

Answers

According to the conflict theory, which was first put forth by Karl Marx, society is constantly at war with one another over scarce resources. According to conflict theory, dominance and power, not agreement and conformity, preserve social order.

The importance of power battles between various factions in influencing society is highlighted by conflict theory. This thesis, which has its roots in Karl Marx's theories, holds that societal development results through conflict between a dominating group and a subservient group.

Pay disparities between groups, as well as disparities in the legal and educational systems of governments, are some instances of conflict theory in action. Interpersonal, role, and other conflicts at work can all be seen through the lens of conflict theory.

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a 2150kg car accelerates from rest over a distance of 18m from a 500N force. what is the final velocity of the car?

Answers

The final velocity of the car that has a weight of 2150 kg and is accelerated by a force of 500 N is 2.8935 m/sec.

What are equations of motion?

There are three equation of motions that can be used when motion of the object is under constant acceleration and on a straight path.

They are listed below as:

v = u + at

s = ut + 0.5at²

v² - u² = 2as

where the symbols have following meanings:

u = initial velocity of the considered object

v = final velocity of the object

a = acceleration of the object

s = displacement done by the object in 't' time.

Given that the force applied on the car is 500 N, while the mass of the car is 2150 kg. Therefore, the acceleration of the car can be found as,

Force = mass × acceleration

500 N = 2150 kg × acceleration

acceleration = 500 N / 2150 kg
acceleration = 0.23256 m/sec²

Further, using the third equation of motion,

v² - u² = 2as

Since the vehicle is at rest initially, u = 0,

v² - 0² = 2as

v² = 2as

v² = 2 × 0.23256 m/sec² × 18 m

v = 2.8935 m/sec

Hence, the final velocity is 2.8935 m/sec.

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How did European colonization of the Aztecs differ from the Incas?Incas resisted because they were more culturally advancedAztecs were treated more harshly than the Incas were.Aztec noblemen were more respected by the SpaniardsAztecs were not decimated by the smallpox as the Incas were.

Answers

The Aztec were mostly taken out by disease; whereas, the Inca were taken out by a large army.

The origins of the Aztecs

The origins of the Aztecs are not known for certain, but they are believed to be a nomadic tribe originating from Aztlan, Northern Mexico. They arrived in Mesoamerica (Mexico and Central America) in the early 13th century, where they are thought to have arrived just after the collapse of the earlier civilization in Mesoamerica, the Toltecs. After spotting an eagle perched on marshy ground near the border of Lake Texcoco, the Aztecs decided to build a settlement. The presence of the eagle is believed to be a sign that they must build settlements on the land.

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Progressives all shared the same goals and approved of the same tactics needed to achieve those goals. true or false

Answers

false Progressives all held the same objectives and supported the same strategies for achieving them.

What did progressives think, and what is progressivism?

Progressivism holds that political action can be utilized to improve human cultures. Aiming to improve society by social reforms that are reportedly based on advancements in science, technology, economic growth, and social structure, progressivism is a political movement.

What possessed the Progressive movement a reputation?

Labor rights, women's suffrage, economic reform, environmental protections, and the care of the poor, especially impoverished immigrants, were just a few of the overlapping concerns that the Progressive Era's leaders worked on.

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weekly calendars are great for listing what type of activities?

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Weekly calendars are great for listing appointments, dates, meals and others

Weekly calendars are great for listing what type of activities?

Weekly calendars are great for listing a variety of activities, including:

Work appointments: These are appointments related to your job, such as meetings, conference calls, or client visits.

Personal appointments: These are appointments related to your personal life, such as doctor's appointments, social events, or family obligations.

Exercise and fitness activities: These include activities such as gym sessions, yoga classes, or outdoor exercise.

Meal planning: You can use a weekly calendar to plan out your meals for the week, including grocery shopping and meal prep.

Errands and chores: This includes tasks such as laundry, cleaning, or running errands like going to the bank or post office.

Hobbies and leisure activities: You can also use a weekly calendar to schedule time for hobbies or leisure activities such as reading, painting, or watching a movie.

Overall, a weekly calendar is a great tool for organizing your time and ensuring that you are able to balance all of the activities and responsibilities in your life.

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Which one of the following statements about microsleep is true?
a. It is a time when a person sleeps at least 60 minutes.
b. It occurs when a person is usually aware it’s happening.
c. It is always safe to do.
d. It appears to help a person survive by preventing total sleep deprivation.

Answers

The given statement "Which one of the following statements about microsleep is true" because It occurs when a person is usually aware it’s happening is the  statements about microsleep therefore the right option is B.

Microsleep is the brief period of the sleep that occurs when the person is in the generally  apprehensive it’s  passing. It  generally happens when a person is in a state of extreme fatigue and isn't  suitable to stay awake. as During this period, the person is  generally being only semi-conscious and is  frequently  ignorant of their surroundings.

It  generally lasts  lower than around 30 seconds and that can  do several times in one day. This brief period of the rest can help the pre-energize the body and reduce fatigue, but it isn't enough to make up for a full night’s rest. The Microsleep can also be very dangerous if it occurs while during driving or the operating heavy machinery.

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why should you not say the public is invited in an editorial context?

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In an editorial context, it's better to avoid using the phrase "the public is invited" because it is informal and lacks precision.

In an editorial context, it's important to use language that is clear and precise. For this reason, the phrase the public is invited should be avoided. This phrase is too informal and does not indicate the exact who, what, when, where, and why of the event.

A more professional way to communicate the invitation to an event is to state the details of the event, including the date, time, and location, and make it clear that the event is open to the public. By providing this specific information, the invitation to the event will be more precise and easier to understand.

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how did the era of industrialization transform american culture?

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In America, Industrialization brought new technology and job opportunities, leading to urbanization and a shift from agrarian to industrial society.

The industrial revolution of the 19th century in America saw a radical shift in the economy, as the country moved from an agrarian society to an industrialized one. This era was made possible due to the emergence of new technology and job opportunities that came with industrialization.

This technological advancement had a ripple effect, leading to urbanization as people migrated to cities for work and greater economic opportunity. Industrialization, then, transformed the country by introducing new technology, creating jobs, and shifting the focus of the economy from rural to urban.

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What does ENTJ mean in Myers-Briggs?

Answers

ENTJ means Extraverted, Intuitive, Thinking, Judging. ENTJs have exceptional problem-solving skills and sharp minds.

They frequently come up with brilliant ideas, are able to analyse the situation from all angles, and carefully lay out a plan to carry out their vision. Problems don't overwhelm them; instead, they give them energy.

Individuals with ENTJ inclinations are frequently intensely driven, competitive, and concentrated. By concentrating on the big picture, they can see just about everything that is going on around them. When given the chance to create long-term objectives and make critically thought-out decisions, ENTJs excel.

Just 2% of people have the INFJ personality type, making it the least common personality type overall. It is also the personality type that guys have the least of. Introversion, Intuition, Feeling, and Judging is referred to as INFJ. It's uncommon to discover this particular combination in most people.

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What is the main point of mountains beyond mountains?

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The main point of Mountains Beyond Mountains is the story of Dr. Paul Farmer, a Harvard-educated physician who has devoted his life to treating infectious diseases in impoverished communities in Haiti and other parts of the world.

The book explores Farmer's dedication to providing healthcare to the poorest of the poor, and his belief that healthcare is a basic human right. It also examines the challenges Farmer faces in his work, including a lack of resources and political instability in the areas where he works. Ultimately, the book is a testament to Farmer's tireless commitment to improving the lives of those who are often overlooked by the healthcare system.

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The mental process of finding an appropriate way to attain a goal when the goal is not readily available as known as?

Answers

The mental process of finding an appropriate way to attain a goal when the goal is not readily available as known as problem solving.

What is Problem Solving?

Problem-solving is the mental process of finding a solution to a problem or challenge. It involves identifying the problem, gathering information, analyzing the situation, and developing and implementing a plan of action to reach a desired outcome. Effective problem-solving often requires creativity, critical thinking, and the ability to consider different perspectives and potential solutions.

The process may involve trial and error, and may require revising and refining the plan until a satisfactory solution is achieved. Problem-solving is an important skill in many areas of life, including work, personal relationships, and decision-making.

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Why did Martin Lawrence get hospitalized?

Answers

Martin Lawrence was hospitalised due to exhaustion and dehydration. According to reports, the actor and comedian had been working non-stop on his various projects, including his stand-up comedy tour and the filming of the Bad Boys 3 movie. This led to him becoming extremely fatigued and dehydrated, resulting in his hospitalisation.

It is important to note that exhaustion and dehydration can have serious health consequences if left untreated. It is important for individuals to listen to their bodies and take breaks when needed in order to prevent such health issues from occurring.

In conclusion, the reason Martin Lawrence was hospitalised was due to exhaustion and dehydration caused by his busy work schedule.

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What is cognitive development theory ?

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According to the Swiss psychologist Jean Piaget's Theory of Cognitive Development, children's intellect evolves as they mature. Children's cognitive growth involves more than just learning; they also need to create or refine a mental model of the world around them.

Cognitive development refers to a child's capacity for thought, exploration, and problem-solving. Children's ability to consider and comprehend their surroundings is aided by the development of information, skills, problem-solving, and dispositions. Cognitive development includes the development of the brain.

Language development is one of the most well-researched aspects of cognitive development. Some theories contend that the ability to learn languages is a genetic trait shared by all people, while others contend that social interactions are crucial for language acquisition.

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When was the last Pandemic Unemployment Assistance (PUA) in Indiana?

Answers

Indiana’s unemployment rate, which bounce to more than 17 percent at the height of the pandemic, has recovered to 3.9 percent. More Hoosiers are in the manpower now than a year ago, and the labor force participation rate is nearing the pre-pandemic level.

“Barring these pandemic programs will not be a silver bullet for employers to find employees, but we presently have about 116,000 available jobs in the state that need filled now,” said Holcomb.

“I’ve declared to leaders in the recreational vehicle industry who tell me they could gave the job to thousands of people today, and in the last couple weeks, we’ve seen companies like Amazon, Apple, Toyota, and Milwaukee Tool announce thousands of new career opportunities for Hoosiers.

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Help ,What happens to the amount of electrical energy that is generated when the specify “a little” or “a lot”

Answers

The amount of electrical energy that is generated in Faucet is on high is "a lot", Faucet is on low is  “a little”.

What do you mean by electrical energy?

When electrons flow from one location to another, they produce electrical energy. Current or electricity is the flow of charged particles along or through a media (like a wire).

In this design, the turbine is powered by the kinetic energy of the flowing water from the faucet. More thermal energy is released into the atmosphere by the steam. a lot of light energy and very little thermal energy are created from this energy.

Therefore, the amount of electrical energy that is generated in:

Faucet is on high is "a lot".Faucet is on low is  “a little”.

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The complete question is attached:

what is fundamental attribution error in psychology?

Answers

Fundamental attribution error refers to the situation on which a person holds the other person accountable for a certain action rather than looking in his own actions.

There are many behavioral aspects when it comes to judging a person. People often judge other people for their actions and hold them accountable for their actions and they ignore their own actions and doings. This is known as fundamental attribution error. This shows that how people easily judge other people even when they themselves are not perfect and often do mistakes. For example, A manager scolds an employee for coming late in office even though he had a genuine reason for that and the next day the manager himself comes lates and did not have genuine excuses for why he came late.

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A trait whose development requires the action of thousands of genes but whose variation is due to variation at only two loci isA.) ExtranuclearB.) DigenicC.) PolygenicD.) Meristic What is the functional group of alcohol and phenol?A) OH Phenol and AlcoholB) Phenol and OH AlcoholC) OH Alcohol and COOH PhenolD) None of the above The Function f(x) is represented below as a graph. Use f(x) to answer the following questions. evaluate f(-2) and determine x when f(x)=1 what is plasma iron polisher ? Square STUV circumscribes circle W. Find the area of the shaded region. Round your answer to the nearest tenth if necessary. From this cross section of the Grand Canyon, what are the oldest rocks or structures? Sir br5. A company is designing a newcylindrical package. The volume ofthe package is 87.92 in.. Theradius is 2 inches. Use 3.14 toapproximate 7 to answer thequestions.Part ATo the nearest inch, how manyinches is the height of thecylindrical package? I need help with the second part Complete the table.Original Price Percent of Discount Sale Price$120 80% $ What does the root word Cerebr o mean? Coach Trevor packs a bag with 16 basketballs and footballs. The rato of basketballs to footballs is 5 : 3. Basketballs weigh 22 ounces, and footballs weigh 16 ounces, How much does the basketballs and footballs weigh in all? Which table shows the relationship between x and y as a direct variation? What are some fiber rich foods that you could add to your diet to increase your intake of both soluble and insoluble fibers? by the mid-eighteenth century, a distinct colonial merchant class came into existence, in part because ofA. Colonial slave codes forbade teaching slaves skilled trades and craftsB. averaged one pregnancy for every two years of marriageC. Higher status than pure Africans in Spanish AmericaD. Illegal colonial trade in markets outside of the British empire What is the value of this expression when c=-4 d= 10 how did peoples general way of thinking change as a result of the scientific revolution? Which example below describes Newton's Third Law: Suppose there is a decrease in the demand for high-definition televisions.The short-run average total cost curve for this product will________ (Increase/Decrease/Not Change)because:a. When demand decreases, the short-run average total cost increases.b. Short-run average total cost depends on workers wage rates and the prices of inputs rather than on demand.c. When demand decreases, the short-run average total cost declines. When other information accompanying audited financial statements contains a material inconsistency that management refuses to revise, the auditor may do which of the following?I Withhold the auditor's report.II. Withdraw from the engagement.III. Include an other-matter paragraph in the report.A. I and II onlyB. I, II, and IIIC. II onlyD. II and III only What is the effect of the poets decision to make charleychaplin one word? It emphasizes the poets keen desire to perform for the audience. It increases the pace at which the reader moves through the line. It suggests that the speaker assumes that readers know the actors full name. It highlights the uncertainty of the audience about whom they are watching.