In an individual with lactate dehydrogenase deficiency, would this [NAD+]/[NADH]ratio be sufficient to lead to a significant, lasting effect on glycolytic flux? Choose one: O A. No. As long as the individual was not attempting high-intensity anaerobic exercise, the mitochondrial shuttle system would quickly restore the steady-state ratio of [NAD+]/[NADH] with minimal effects on glycolytic flux. O B. Yes. NAD+ is required for the glyceraldehyde-3-phosphate dehydrogenase reaction, which is already unfavorable under standard conditions. Further reducing the concentration of NAD+ would make this reaction even more unfavorable under cellular conditions, and this reaction would therefore not be able to proceed in the forward direction. Glycolytic flux would be significantly affected as a result. C. No. The [NAD+]/[NADH] ratio has very little effect on glycolytic flux. The lactate dehydrogenase reaction is more important for preventing the buildup of pyruvate under anaerobic conditions, which can lead to inhibition of the pyruvate kinase reaction. As long as the mitochondrial oxidation reactions are able to reduce the concentration of pyruvate, the NADH concentration is not very important. O D. Yes. Glycolytic flux is very sensitive to the [NAD+]/[NADH] ratio, and any movement away from the steady- state value would cause a significant disruption to glycolytic flux.

Answers

Answer 1

B. Yes. NAD⁺ is required for the glyceraldehyde-3-phosphate dehydrogenase reaction, which is already unfavorable under standard conditions.

Further reducing the concentration of NAD⁺ would make this reaction even more unfavorable under cellular conditions, and this reaction would therefore not be able to proceed in the forward direction. Glycolytic flux would be significantly affected as a result.

The glycolytic pathway is responsible for the breakdown of glucose to pyruvate, with the concomitant production of ATP and NADH. The oxidation of NADH to NAD⁺ by the mitochondrial electron transport chain is necessary to maintain the activity of glycolysis by maintaining a favorable [NAD⁺]/[NADH] ratio. In lactate dehydrogenase deficiency, the conversion of pyruvate to lactate is impaired, resulting in the accumulation of NADH and a decrease in the [NAD⁺]/[NADH] ratio. This decrease in the ratio would lead to a decrease in the activity of the glyceraldehyde-3-phosphate dehydrogenase reaction, which is already unfavorable under standard conditions. As a result, the forward flow of the glycolytic pathway would be inhibited, leading to a decrease in glycolytic flux. Therefore, the correct answer is B. Yes, as the [NAD⁺]/[NADH] ratio has a significant effect on glycolytic flux.

learn more about glucose here:

https://brainly.com/question/30970595

#SPJ11


Related Questions

differentiate between thallophyta bryophyta and tracheophyta​

Answers

Answer:

The main difference between Thallophyta Bryophyta and Pteridophyta is the organization of each phylum. Thallphyta consists of algae, fungi, lichens, and cyanobacteria. The plant body of Thallophyta is a thallus. ... The plant body of bryophytes is not differentiated into true stem, roots, and leaves.

Explanation:

Sister chromatids are ____.. Single choice.

A. dense patches within the nucleus
B. bacterial chromosomes
C. joined strands of duplicated genetic material
D. prokaryotic nuclei
Option 2

Please hellppppp!

Answers

the answer is C i hope it’s right but i searched up

Answer:

C- joined strands of duplicated genetic material

Explanation:

key words duplicated sister

Which of the following statements about viruses is true?
A: A virus belongs to the Archaea Domain.
B: A virus is a single-celled organism.
C: A virus has a cell membrane made of proteins.
D: A virus can evolve.

Answers

Answer:

D: A virus can evolve.

Explanation:

Viruses are not organisms so that rules out all other options.

It is proper to put the _____________ allele before a recessive allele when determining the genotype of the offspring in a Punnett square.

Answers

Answer:

dominant

Explanation:

the dominant allele is the capital letter (for example, T) whereas the recessive allele is the lowercase letter (for example, t). the dominant allele is usually written first.

It is proper to put the dominant allele before a recessive allele when determining the genotype of the offspring in a Punnett square.

What are alleles?

Alleles are the variation present in the gene or DNA sequence. It is the sequence of nucleotides that encodes the production of the product of a gene.

There are two types of alleles, dominant and recessive, the dominant gene is denoted by a capital letter, and it is placed before the recessive allele.

Thus, in a Punnett square, the dominant allele should come before the recessive allele when determining the genotype of the offspring.

Learn more about alleles, here:

https://brainly.com/question/18075358

#SPJ2

What is the name of the site of transcription?

1. Amino acid
2. Nucleus
3. Cytoplasm
4. Mitochondria

Answers

The eukaryotic nucleus therefore provides a distinct compartment within the cell, allowing transcription and splicing to proceed prior to the beginning of translation. Thus, in eukaryotes, while transcription occurs in the nucleus, translation occurs in the cytoplasm.
The Nucleus is where transcription occurs.
B. Nucleus

hope this helps

7._________________________ lines your digestive tract and blood vessels. It moves food and blood through your body.

smooth muscle
skeletal muscle
cardiac muscle

Answers

Answer:

Smooth Muscle

Explanation:

In the digestive tract it's called the muscularis mucosa.

What leads to variation in a population?​

Answers

Answer:

Genetic variation can be caused by mutation (which can create entirely new alleles in a population), random mating, random fertilization, and recombination between homologous chromosomes during meiosis (which reshuffles alleles within an organism's offspring).

Explanation:

3 questions


1. Water vapor needs ____ to become rain or snow

a. humidity

b. cool air

c. dust

d. all of the above


2. water droplets fall because they are too ?

a. warm

b. cool

c. heavy

d. cold


3. snow is formed when water droplets

a. form ice crystals

b. melt slightly

c. stick together

d. all of the above


These questions are worth 25 points first one to answer CORRECTLY gets marked brainliest :) good luck

Answers

Answer:

the answers are

1) b

2)c

3) a

Water vapor needs cool air, dust particles, and humidity to become rain or snow. Thus, the correct option is D.Water droplets fall because they are too heavy. Thus, the correct option is C.Snow is formed when water droplets form ice crystals. Thus, the correct option is A.

What is Water vapor?

Water vapor may be defined as the gaseous form of water that is usually dispersed across the atmosphere with the help of wind. This state of water is significantly found in the hydrosphere.

This gaseous form of water is formed from the evaporation or boiling of liquid water or from the sublimation of ice.

Water vapor requires to combine with dust particles and cool air along with atmospheric humidity in order to produce rain or snow. Due to the combination of such compounds, water droplets become too heavy.

Snow or ice is the solid appearance of water which is usually formed from the compaction of crystallized structure.

Therefore, each of the above questions is described.

To learn more about Water vapor, refer to the link:

https://brainly.com/question/11226635

#SPJ6

How do antibiotics work? Note: you will not be given credit for simply stating “they prevent bacterial growth” or “they kill bacteria”

Answers

Antibiotics stop infections caused by bacteria, they kill it , and/or keep them from copying themselves or reproducing . antibiotic means against life, so any drugs in your body is technically an antibiotic. they attack the wall or coating surrounding the bacteria

Answer:

here's your answer

Explanation:

May this helps you..

How long will it take a cross country runner to cover a distance of 350 meters at a speed of 17.5 m/min?

Answers

Answer:

20 minutes

Explanation:

Divide distance by speed to get time

D/S = t

350/17.5 = 20

(Just an fyi you posted this in biology)

How many moles are present in 10, 0 grams of sodium hydroxide (NaOH )

Answers

Answer:0.250 mols

Explanation:

That’s the answer I got it wrong using the guy that previously wrote that the answer is 19 mols his totally wrong don’t trust him

We have that Moles that  are present in 10, 0 grams of sodium hydroxide (NaOH ) is

Moles\ NaOH =0.25moles

From the question we are told

How many moles are present in 10, 0 grams of sodium hydroxide (NaOH )

Generally the equation for the  Molar mass of sodium hydroxide is

[tex](NaOH) = (22.990 + 15.9994 + 1.008) \\\\ {(NaOH)} = 40 g/mol[/tex]

Where

Mass_{NaOH}taken = 10 g.

[tex]Moles\ NaOH =\frac{(mass of NaOH taken)}{(molar mass of NaOH)}\\\\Moles\ NaOH = \frac{10}{(40}\\\\Moles\ NaOH =0.25moles[/tex]

Therefore

Moles that  are present in 10, 0 grams of sodium hydroxide (NaOH ) is

Moles\ NaOH =0.25moles

For more information on this visit

https://brainly.com/question/17756498

What would happen to the production of the high energy sugars if water or carbon dioxide were not
available to plants?
ATD

Answers

Answer:

There would be no production of high energy sugars in the plant.

Explanation:

Plants produce their food (autotrophism) in a process unique to them called PHOTOSYNTHESIS. Photosynthesis is the process whereby plants produce energy-storing sugars (glucose) in the presence of light from sun.

This photosynthetic process combines Carbon dioxide (CO2) and water (H2O) as reactants to form sugar (C6H12O6) and oxygen (O2) as products. The equation for photosynthesis is as follows:

6CO2 + 6H2O → C6H12O6 + 6O2

This means that water and carbon dioxide are strictly needed for the process of photosynthesis to occur in plants. Hence, if water or carbon dioxide were not available to plants, there would be no photosynthetic process and ultimately no production of high energy sugars.

Precautions to take during potato osmosis lab

Answers

First, Take a deep enough cavity which can keep a thin layer of tissue at the base of the potato. Second, Make sure the sugar solution which you use, should be sufficiently high osmotic concentration compared to the cell sap of potato cells.

Can someone help with this ?

Answers

Answer:

to convert ADP to ATP

= first option

Explanation:

so it must be the first option

since in order for this conversion the process stated in the first option must occur.

Which process involves starting with a DNA message and ending with mRNA?
a. replication
b. transcription
c. translation
d. translocation

Answers

I think its c. Translation
B because the mRNA is like a transcript or copy of the gene’s DNA code.

Which of these structures do plants and algae have in common?

A. phloem

B. stems

C. chloroplasts

D. xylem

(pls answer this and have a good day)

Answers

Answer:

b and c

Explanation:

Necesito hacer un mapa mental sobre taxonomia y fuandamento filosofico como lo puedo hacer me ayudan plis es urgente

Answers

Answer:

A taxonomy map of philosophy is created using 5 layer version

Explanation:

The map is drawn in a circular form, the parent is usually the center and then the child or the sub branches are then made around the first- parent circle to show the relation between the parent and its child. These branches can have their own sub branches which are then included around the branches the child of the original parent.

HELPP
The diagram below shows the similarities and differences of plants and animals complete the diagram by filling in the correct term as follows: heterotrophic and autotrophic and multicellular

Answers

Answer:

Both are multicellular (plants have different cells for the leaves and the stem, animals have skin cells, brain cells etc so they are called multicellular).

Plants are autotrophic - they make their own food (glucose) by photosynthesis

Animals are heterotrophic - they eat other organisms, cannot make their own food.

Explanation:


What effect does the deer's behavior have on the survival and reproduction of these two
types of cactus?

PLS HELP

Answers

Answer:

Greatly affected.

Explanation:

The deer's behavior has greatly affected the survival and reproduction of these two  types of cactus because one cactus is eaten by deer while the other is saved from it. The cactus with no spines are eaten by deer which destroy the vegetative as well as reproductive parts of cactus so its survival and reproduction does not occur whereas the other cactus have spines on its body is save from deer and increase in the chances of survival and reproduction occur.

a nerve blank is an electrical signal that flows through the nervous system

Answers

Answer:

A nerve is a collection of cells that send messages to your brain, this signal is chemical energy a nerve blank however can be an alternative name for this.

Explanation:

What does semiconservative replication refer to?
a
Both strands are new in each new DNA molecule.
Both strands are conserved in each new DNA
molecule.
с
One strand is conserved and one strand is new in
each new DNA molecule.
d none of the above

Answers

Answer:

it is a

Explanation:

Both strands are new in each new DNA molecule.

Recessive traits are...


visible in the organism's phenotype as long as TWO recessive traits are present.


visible in the organism's phenotype as long as ONE recessive trait is present.

Answers

I don’t really understand this question can you go more into detail

In a herd of beef cattle, the average yearling weight of all animals was 800 lb when corrected to a bull basis. Bulls and heifers kept for breeding weighed 1000 and 825 lb, respectively. The progeny of those individuals selected for breeding had an average yearling weight corrected to a bull basis of 845 lb. What is the apparent genetic control of the trait

Answers

Answer:

Explanation:

The trait is genetic and not dependent on environment. When a trait is dependent on the genetic component of the parental generation, the ability of the traits to be passed from a generation to another is high and this will be revealed in their resemblance with the parent. Hence, the case of the offspring with an average weight of 845lb.

If the trait is controlled or influence by the environment there will be a difference when the offspring is produce because until the same environment is given to the offspring the trait cannot be expressed.

How is the brain involved with the senses and what is the relationship to the wat a personreacts to objects?

Answers

Answer:

The senses are the components of our nervous system that capture stimuli from the environment for transmission to the brain, and it is there where the information is processed to issue a response. All sensations are electrical signals that travel through neurons which form a network that communicates all organs with the center of the nervous system, and communicate with each other to transmit the electrical impulse through a process known as synapsis.

Explanation:

The brain is an organ that controls the activity of the body, both its conscious and unconscious functions. It is located in the head and corresponds, therefore, to the encephalon of humans and other vertebrates and is subdivided into forebrain, midbrain and hindbrain.  

The brain acts on the rest of the organism by generating muscle activity or by the production and secretion of chemicals called hormones. Thereby the brain controls responses to changes in the environment. Some basic types of response such as reflexes may be mediated by the spinal cord or peripheral ganglia, but sophisticated intentional control of behavior based on complex sensory information requires the integration of information.

The thalamus, which is located in the central part of the brain, processes and coordinates the messages from the senses that it receives from the body. Five senses are considered to exist: sight, touch, smell, taste and hearing. For that, the information perceived from the outside must reach the brain.

The senses are the components of our nervous system that capture stimuli from the environment for transmission to the brain, and it is there where the information is processed to issue a response. Therefore, all sensations perceived from the outside are electrical signals that travel through neurons. For example, the eyes transform light signals into electrical impulses, which travel to the brain where they are transformed into electrical signals.

Neurons form a network that communicates all organs with the center of the nervous system, and communicate with each other to transmit the electrical impulse through a process known as synapsis, which is mediated by molecules called neurotransmitters. Since the electrical impulse cannot jump directly from one neuron to another, these neurotransmitters are needed. When the active neuron produces them, the next neuron in the network detects them and becomes electrically charged. Once this has happened, it produces neurotransmitters again so that the next one becomes electrically activated. This is how the electrical impulse reaches the brain.

4. What domain name should replace the question mark in this chart?
5 points
Unicellular Protozoa
Uni/multicellular
algao
Multicollular
heterotroph
cell walls chitin
?
Multicoulluar
autotroph
cell walls
of cellulose
Multicellular
heterotroph
Lack cell walls
O a. Archaea
b. Bacteria
O c. Eukarya
O d. Monera

Answers

Answer:

C. Eukarya

Explanation:

Note: your teacher will review your response to this question to ensure you receive proper credit for your answer. The pH scale is a measurement system that indicates the concentration of _______ in solution.
please help ​

Answers

Answer:

hydrogen and hydroxide ions

Explanation:

The pH scale indicates the concentration of hydrogen ions (H+) and hydroxide ions (OH-) in a solution.

15 Which of the following mutations would have the potential to affect future
generations of a species?
A A frame shift mutation in the X chromosome of a cheek cell
B A chromosomal mutation in the Y chromosome of a kidney cell
CA point mutation in the first chromosome of a sperm cell
D A substitution mutation in the third chromosome of a uterus cell

Answers

Answer:

c i think

Explanation:

I don't know just trying to help hope you have a good day

The answer is c a point mutation in the first chromosome of a sperm cell

Please help!!!! Grizzly bears and polar bears are very closely related, so much so that they can reproduce to form hybrid offspring. Use your understanding of natural selection to describe how polar bears became a separate classification from the grizzly.

Answers

Scientists believe that at first these bears scavenged seal carcasses that had washed ashore, and gradually began to hunt the seals by waiting at the water's edge as the seals surfaced to breathe. This is believed to be an important step in the evolution of a new bear species, the polar bear

Over time the new polar bears were used to the cold climate and learnt how to fish, they then separated from the grizzly bears, they developed new creatures which would help them survive in one of the most dangerous climate.

Polar bears become separate classification from the grizzly by the natural selection known as divergent and adaptive evolutionary change.

Polar bears and grizzly bears are considered as closed to one another so they can interbreed. They both diverged from one another due to the harsh climate of the Arctic and the ecology of the region.

The changes that took place are camouflaging and pigment-free fur-coat that helped them in order to adapt to the different climates.The genetic mutation leads to such Adaptive changes when the polar bears migrated northwards.The populations living in different climates undergo natural selection that is divergent natural selection and the adaptive evolutionary changes that result in different species.

Learn more about speciation:

https://brainly.com/question/4493180

please help me with this biology question.............


Why is the use of electron microscopy important in studying cells ??​

Answers

Explanation:

Electronic microscope helps us to see each every part of the cell. So, it is considered important

Answer:

A cell is the smallest unit of life. Most cells are so small that they cannot be viewed with the naked eye. Therefore, scientists must use microscopes to study cells. Electron microscopes provide higher magnification, higher resolution, and more detail than light microscopes.

Explanation:

hope it's help you

While exploring a rock formation, Hiroto finds a rock that has footprints pressed into it. A geologist tells Hiroto that the rock is millions of years old. Which of these claims
is correct about Hiroto's find?
It is not a fossil because footprints are not fossils.
It is not a fossil because only whole organisms are fossils.
It is a fossil only if Hiroto finds actual parts of the organism in rocks nearby.
It is a fossil because footprints of organisms from million of years ago are considered to
be fosss

Answers

Answer:

5 is the answer

Explanation:

Answer:

message me on ig

Explanation:

she.hatezay ill help you there

Other Questions
Help me pleaseeeeeeeeeeeeeeeeeee What fraction is less than 1/2. 3/4,1/6,6/12,4/10,5/8,5/2 The _______ was a naval battle in which the British and Dutch were able to maintain a blockade of German ships. The last major battle of World War I was _______. World War I ended with the _______, which was like a truce. The name of the organization of nations whose purpose was to solve conflicts peacefully through negotiations was known as _______. _______ were first used in World War I because they were needed to cross the muddy and uneven terrain in Europe. Germans used _______ to try to match the might of the powerful British navy. The medical advance that saved soldiers' lives by helping to reset broken bones was the _______. PLEASE HELP !! ILL GIVE BRAINLIEST *EXTRA POINTS*.. IM GIVING 40 POINTS !! DONT SKIP :((. 35= h(b1+b2) solve for b2 Highlight any four contributions of natural resources towards the economics development of Ghana Which of the following was not a cause of the Great Migration?A. Rumors of a life of luxury in the New WorldB. A political crisis in EnglandC. Unemployment in EnglandD. Religious persecution Enter the value of 2 (4x + 3) when x = 3. Which is one of the Lewis structures for ozone?000:0:00C:6 so anyone need to handle this id Barrios Communications is a provider of satellite television services. It will install a satellite dish free of charge for any customer that agrees to a one-year service contract at a price of $50 per month. Installation costs Barrios $150. Customers typically remain with Barrios for much longer than the one year required, an average of 10 years (i.e., 9 years beyond their contractual obligation). Barrios enters into a contract under the terms described above on January 1, 20X1. Required:1. What amount of revenue should Barrios record related to the contract in 2019?2. What amount of expense related to the contract should Barrios record related to the contract in 2019? If r = .15, this indicates 5 for $4.45 or 8 for $7.28 41,692.58Which number is in the tenths place?A. 2B. 5C. 8D. 9 Please help me find the main idea my teacher about to call on me and i am pi ss A week after the murders, police raided Spahn Ranch, but not because of those heinous crimes. Manson and most of the family were arrested instead for stealing cars. But they were released on a technicality and fled to Death Valley. There, they were arrested again in multiple waves of police raids between Oct. 10 and 12, 1969. In addition to a series of thefts and generally terrorizing the locals, Manson had set fire to some heavy equipment owned by Death Valley National Monument rangers, which was what really brought the cops down on the family [source: Sanders]. Use properties of operations to determine whether or not the expressions (x + 10) + x + 9 and 2(x + 7) + 5 areequivalent Before Rosa parks there was Claudette Colvin. Which quote from the text best supports to answer to part A PLEASE IS MY LAST QUESTION WILL GIVE BRAINLIEST Using the formula :Force Distance = Work Perfomed , Match the Force Distance problems with their correct Work Performed answer? Childrens books are an example ofhow images and words work togetherhow graphic design can be misleadinghow graphic design makes ideas unclearhow only young children appreciate graphic design