Epinephrine acts as a signal molecule that attaches to _____ proteins.

Answers

Answer 1

When it binds to G-protein-linked receptor proteins, epinephrine functions as a signal molecule.

What function does cAMP serve in the epinephrine-activated signal transduction pathway?

What part does cAMP play in the signalling process? Correct This response option is appropriate since cAMP is a second messenger that transmits information from G protein-coupled receptors to the start of the phosphorylation cascade.

What is the cause of the beginning of a signal transduction pathway?

When G-protein molecules linked to the adrenergic receptor activate the membrane-bound enzyme adenylyl cyclase, the signal transduction cascade starts. The numerous cyclic AMP molecules produced by adenylyl cyclase fan out and activate protein kinases (PKA, in this example).

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Related Questions

16,17The use of these established cell lines have been increasinly replaced with primary cell cultures given that the latter better represent the in vivo cancer cell behaviours.

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A Final statement or concluding statement

Tumor cells have experienced a variety of genetic and epigenetic changes as compared to normal cells. Because these alterations frequently underpin cancer genesis, progression, and therapy resistance, the efficacy of model systems is dependent on their capacity to replicate the genetic abnormalities seen in original tumors.

Tumor-derived cell lines have long been utilized to explore the underlying biologic processes in cancer, as well as as screening platforms for identifying and assessing anticancer treatment effectiveness.

Following advancements in high-throughput technology and multigroup collaborative efforts, several -omic measurements across over a thousand cancer cell lines have been produced. These findings supplement large-scale worldwide cancer genomic sequencing initiatives to define patient malignancies, such as The Cancer Genome Atlas (TCGA) and the International Cancer Genome Consortium (ICGC) (ICGC).

Individual data analysis or data integration methodologies will provide an increasing number of hypotheses to examine. Cancer cell lines will continue to be useful in this context and will play an important part in cancer biology research in the future.

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The pathway by which carbon is transferred from the atmosphere to plants is called:_______

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photosynthesis is the answer

A____is a musculoskeleteal injury in which there is a partiral or temporay seperation of the bone ends as well as partial tretdhcing or teaing of the supporting ligamentes

Answers

Dislocations is a musculoskeletal injury in which there is a partial or temporary separation of the bone ends as well as partial tearing of the supporting ligaments .

4 types of musculoskeletal injuries includes repetitive strain injuries (RSIs), repetitive motion injuries, cumulative trauma disorders (CTDs), work-related upper limb disorders (WRULDs).

Most common type of musculoskeletal injury is Muscle Strains, back pain, and arthritis . Muscle strains can happen due to improper technique of lifting heavy objects, lifting too much weight at one time, and repetitive movements. The key symptoms of a muscle strain are sudden pain that worsens while contracting the muscle, swelling and bruising, loss of strength and range of motion. People often report the sensation of pain as the feeling of being "stabbed." When muscle is initially injured, significant inflammation and swelling occurs.

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Which fact supports the conclusion that there will be fewer farm managers in the future?

Administrative duties include budgeting and training staff.
Farm technology is replacing some administrative jobs.
Farm managers often need experience but not education.
A farmer manager’s duties vary by the type of farm.

Answers

Answer:

I think that it is the 2nd one

Therefore, when the alleles of a particular gene are passed on to their descendants via gametes, a haploid sperm fertilizes a haploid egg producing a ____________ .

Answers

Therefore, when the alleles of a particular gene are passed on to their descendants via gametes, a haploid sperm fertilizes a haploid egg producing a diploid zygote.

The process in which haploid gametes fuse to form diploid offspring:

A diploid cell produces haploid cells during meiosis, and two haploid cells (gametes) combine during fertilization to create a diploid zygote.

Meiosis is a type of cell division in sexually reproducing organisms that reduces the number of chromosomes in gametes, which results in the production of gametes, such as sperm or egg cells. Meiosis comprises two rounds of division, producing four cells with only one copy of each chromosome as a final product (haploid). Additionally, each chromosome undergoes genetic material cross-pollination between the paternal and maternal copies before division, resulting in novel combinations of the genetic code on each chromosome.  The haploid cells created by meiosis between a man and a female will later unite during fertilization to create a cell with two copies of each chromosome once more, the zygote.

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In which of the domains would it be easiest to determine the phylogenetic relationships among organisms?

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The study of relationships and the evolutionary history of various groupings of species is known as phylogeny. The goal of phylogeny is to reconstruct the evolutionary course of all species on Earth. A phylogenetic tree also learned as a cladogram, is a schematic diagram used to show the alleged evolutionary relationships between taxa. Diagrams of phylogenetic trees are based on cladistics, or phylogenetic systematics, hypotheses.

Organization of life, according to taxonomy, divides creatures into three domains:

BacteriaEukaryaArchaea

The Eukarya domain are the most easy because they are large enough for their morphological features to be easily seen.

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Which statement best describes the cell membrane?
1. It is found only in animal cells
2. It is a nonliving structure
3. It controls reproduction in a cell
4. It controls the passage of materials into the cell

Answers

Answer:

The correct answer is 4

Explanation:

The cell membrane, also called the plasma membrane, is found in all cells and separates the interior of the cell from the outside environment. The cell membrane consists of a lipid bilayer that is semipermeable. The cell membrane regulates the transport of materials entering and exiting the cell.

Hope this helps you

Researchers conclude that the functional car8 enzyme decreases pain signaling by inhibiting calcium release through itpr1. which additional finding would most weaken this conclusion?

Answers

The additional finding that  weaken this is the presence of another factor capable of both altering car8 activity and leading to the inhibition of calcium release.

What are pleiotropic effects?

The expression 'pleiotropic effects' makes reference to a given chemical substance or compound (in this case, for example, another enzyme) which is able to alter the functioning of different cellular traits.

These effects (pleiotropic effects) are well known in research to mask the real causes of biological phenomena.

In conclusion, the additional finding that would most weaken this conclusion is the presence of another factor capable of both altering car8 activity and leading to the inhibition of calcium release through itpr1.

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What is a biochemical ​

Answers

Answer:

Biochemistry is the branch of science that explores the chemical processes within and related to living organisms.

Answer:

Glucose is an example of a biochemical compound. The prefix bio- comes from the Greek word that means “life.” A biochemical compound is any carbon-based compound that is found in living things. Biochemical compounds make up the cells and tissues of living things.

What is the correct order for the events that occur during a reflex? a: impulse travels through sensory neuron to the cns b: a stimulus activates a receptor

Answers

The correct reflex order is a stimulus activates a receptor and than impulse travels through sensory neuron to the CNS.

The reflex arc is composed of sensor, sensory neuron, control middle, motor neuron, and muscle. these elements paintings as a relay group to take facts up from the sensor to the spinal twine or mind and go into reverse to the muscle tissues

A reflex movement frequently entails a totally simple fearful pathway referred to as a reflex arc. A reflex arc starts with receptors being excited. They then send indicators alongside a sensory neuron to your spinal cord, where the signals are exceeded directly to a motor neuron.

A reflex action is a way for the body to automatically and hastily reply to a stimulus to any further damage to the frame. It follows this widespread series and does no longer involve the brain: stimulus → receptor → sensory neurone → relay neurone → motor neurone → effector → response.

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The correct order of reflex is b) and then a) i.e. impulse travels through sensory neuron to the CNS and a stimulus activates a receptor.

In a reflex, a stimulus activates a receptor and the information travels through a sensory neuron to the Central Nervous System (CNS).

A receptor is a cell that responds to a stimulus like light, heat or pain.

An impulse is the signal that travels through the neurons from affector to effector.

The information is carried out through a sensory neuron which connects the receptor and the CNS.

CNS comprehends the information and send the signals to the effector through the Motor Neuron.

Motor neuron is a neuron that carries information from CNS to the Effector cells, i.e. which responds to the stimulus.

The motor neuron transmits information to the effector cells and hence the reflex arc is completed after the response.

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Some allergens act directly as ______, and the immune system recognizes them as foreign, stimulating the production of specific antibodies.

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Some allergens act directly as antigens, and the immune system recognizes them as foreign, stimulating the production of specific antibodies.

What is immune system?The body's defense against infection is provided by the immune system, a complex network of organs, cells, and proteins that also safeguards the body's own cells. Every germ (microbe) that the immune system has ever eliminated is recorded, allowing it to promptly identify and eliminate the microbe if it re-enters the body.Flu, mono (mononucleosis), and measles illnesses can temporarily impair immune function. Additionally, unhealthy eating habits, alcoholism, and smoking might impair your immune system.Since the many types of immune system cells are produced in the bone marrow, if the immune system were a police force, it would be the police academy. In the bone marrow, stem cells, a common type of beginning cell, are used to develop all immune system cells.

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What is the best evidence to
prove that Irene was heterozygous for hemophilia?
Elizabeth IS not a carrier for the trait.
Tatiana carried the recessive allele.
Her brother has
hemophilia and her sister is a carrier.
Two of her sons have hemophilia and one does not.

Answers

The best evidence would be two of her sons having hemophilia while one does not.

Hemophilia

Hemophilia is a sex-linked recessive disorder. This means that females can be homzygous normal, heterozygous, or affected by the disorder while males can either be normal or affected.

Why? This is because males have only one X chromosome (XY) while females have 2 X chromosomes (XX).

Also, the X chromosomes in males are always from their mothers while their Y chromosomes come from the father.

So, if the two X chromosomes of Irene are normal for hemophilia, none of her sons should be affected. If the two X chromosomes are affected, all her sons will have the disorders.

When one X chromosome is affected and the other is normal, it means that some of her sons will inherit the affected chromosome and have the disorder while some will inherit the normal chromosome and will be free from hemophilia.

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The strongest evidence that Irene is heterozygous for the condition is the fact that two of her boys have hemophilia and one does not. Because hemophilia is an X-linked recessive disorder, the X chromosome plays a role in its genesis. Males only have one X and one Y chromosome, whereas females have two X chromosomes.

If Irene were homozygous for the normal allele (non-carrier), none of her boys would receive an incorrect X chromosome, preventing them from developing hemophilia. If Irene were homozygous for the hemophilia allele (affected), all of her sons would be affected by the disease since they would inherit her X chromosome.

However, Irene may be a carrier of the hemophilia allele given that two of her sons have the condition while one does not. As a transporter, she has one typical X chromosome and one X chromosome conveying the hemophilia allele. She can pass either the typical or the hemophilia allele to her posterity, bringing about a blend of impacted and unaffected kids.

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The features and impressions of freestanding sculpture change according to the __________.

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The features and impressions of freestanding sculpture change according to the position of the viewer.

What is Sculpture?

This aspect of visual arts operates in three dimensions which include the following:

HeightWidthDepth

The features which include how a sculpture is viewed is dependent on the position of the viewer as every human is unique thereby making it the most appropriate choice.

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Cone pigment gene expression in individual photoreceptors and the chromatic topography of the retina.

Answers

In every cone cell, there was only one photopigment gene that is expressed. A specialized light sensor known as a cone is found in and around the Fovea structure in the retina of the eye.

Discussion about the statement -

L, M, and S cones are the three types of cones that make up human trichromatic vision (long-, middle-, and short-wavelength sensitive, respectively).In addition to an S pigment gene located on chromosome 7, individuals might have multiple M, multiple L, or multiple S pigment genes on the X chromosome. The polymorphic variations of the X-linked pigment gene array in certain individuals can encode numerous, spectrally different cone photopigment subtypes. The outcomes also demonstrate that the expression of the various pigment genes within a single array frequently varies greatly, leading to an uneven distribution of L and M cones. Individual guys, however, may have more cone types in their retinas than the three spectrally different cone types that are often characterized.

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Holding your breath while ascending can lead to: Select one: A rupture of the tiny air sacks in the lungs, known as alveoli. A lung overpressure (overexpansion) injury. Arterial gas embolism (AGE). All of the above.

Answers

Holding your breath while ascending can lead to all of the above options.

Surfacing excessively fast or holding the breathing while swimming to the surface can make the air in the lungs expand which is known as pneumonic barotrauma. This might break lung tissue, which can prompt gas bubbles to be delivered into the blood vessel dissemination (arterial gas embolism).

The air in the lungs becomes risky when an individual ascends. On the off chance that somebody holds their breath while rising to the surface, the lungs and the air inside them extend as the water pressure decreases. Since that air has no place to escape, it continues to expand against the walls of the lungs, no matter what the organ's capacity.

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Which statement BEST describes how greenhouse gasses act as natural insulators in the Earth's system?

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Hi there, your answer is below.

The gases absorb and emit a part of the heat reflected by the Earth's surface.

Solar radiation will pass through the atmosphere first in the greenhouse effect. Some of them will get through and touch the surface of the planet. Long-wave thermal radiation, which is what the greenhouse gases will absorb, will be produced when some of the energy that strikes the Earth's surface is transformed. They are returned to the Earth via greenhouse gases.

What are greenhouse gases, and why do they affect our environment?

The surface of the Earth would be much colder and have a "snowball Earth" if it weren't for the impact of greenhouse gases, primarily water vapor, carbon dioxide, and methane.

Because the greenhouse gases are generally transparent to the sun's incoming radiation, which is mostly in the visible light region of the spectrum, the greenhouse effect is able to take place. In contrast, the majority of the radiation that the Earth emits is in the infrared region of the spectrum, which is absorbed by greenhouse gases. Some of the radiation from these gases is redirected to the earth when it is later released. This traps it, warming the planet's surface in the process. The average temperature of the Earth would be -14 degrees Celsius without greenhouse gases.

Greenhouse gases have acted to even out temperature changes over Earth's history. Huge woods have thrived when the Earth experienced warmer times, as the Carboniferous epoch. These have taken in carbon dioxide from the air, storing the resultant carbon in the form of coal deposits underground. After a certain amount of carbon has been stored, the atmospheric concentration of carbon dioxide falls to very low levels, and the warming effect is eliminated. The trees perish as the globe cools.  Currently, plants are no longer removing carbon dioxide from the atmosphere, while volcanoes are still adding carbon dioxide to the atmosphere. The increase in carbon dioxide causes a rise in global warming. We are now recuperating from the last glacier, which ended roughly 10,000 years ago, during a mild time. In the past 120,000 years, the previous warm era peaked.

The ability of carbon dioxide to boost plant development is another crucial effect. Without the impact of the increased carbon dioxide concentration on crops, it is improbable that the Earth could support the 7 billion people that inhabit it now.

The amount of carbon stored in the atmosphere is rather tiny. There are currently 800 billion tons of carbon in it. But only approximately a quarter of this, or 210 billion tons, of the carbon gets recycled each year by plants and the seas. Consequently, the two-year half life of carbon in the atmosphere is rather short. Because there is such a tiny atmospheric carbon storage, people have a significant impact. Burning fossil fuels only adds roughly 9 billion tons annually. But throughout my lifetime, the concentration has increased by 30%, from around 300 parts per million in 1947 to 410 parts per million now, as a result of this modest increment each year. As a result, there has been a little but considerable increase in surface temperature as well as rising sea levels due to ice cap melting. Although the increase in sea levels over the past 70 years has only been around 9 inches, it is rising, and because so many people live near the coasts, we are susceptible.

Because the atmospheric carbon storage is so limited, it is possible to lower atmospheric carbon and prevent flooding in our coastal communities, for example by fertilizing the seas to improve their capacity to absorb carbon dioxide.

Thank you,

Eddie

Some bacteria have been found to have much higher rates of mutation than other members of their population; they are termed "mutators." What do you think is the most likely reason for their higher rates of mutation?

Answers

Their DNA polymerase has compromised 3' to 5' exonuclease function.

Polymerase

An enzyme that builds lengthy nucleic acid or polymer chains is called a polymerase. Using base-pairing interactions to copy a DNA template strand, DNA polymerase and RNA polymerase build DNA and RNA molecules, respectively, while half ladder replication builds DNA molecules.

For the polymerase chain reaction, a crucial molecular biology method, the thermophilic bacteria Thermus aquaticus' DNA polymerase is used. Template dependence or independence are two possible states for a polymerase. Template independent polymerase examples include poly-A-polymerase. Both template independent and dependent activity are known to exist for terminal deoxynucleotidyl transferase.

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Based on the ratios in the f2 population, how many genes are involved in the production of color?

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There are many traits in human which is determine by polygenic inheritance such as skin co-lour, hair co-lour, eyes co-lour, height , risk for diseases and resistance , intelligence, etc.

Inheritance of skin pigmentation is polytechnic inheritance .In thee F2 generation -AaBbCc * AaBbCc mate they varying range from dark to very light ,F2 generation of two triple hetero-zygotes.

Punnet square showing F2 generation offspring continuous variation.The expression of poly-genes is greatly influenced by environment conditions.There are genetically basis for human skin co-lour because of more than 100 different genes involved which produce melanin pigment which responsible for co-lour of a person.

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An amoeba is much less complex than a fruit fly; however the amoeba has a much larger genome (c-value). What is the best overall explanation for this paradox?

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The amoeba has a much larger genome (C-value) because A large percentage of eukaryotic genomes is non-coding DNA, the amoeba has much more non-coding DNA than the fruit fly.

The amount of DNA in an organism's haploid genome is measured by the C-value. It varies greatly, often rising in C-value as organism complexity increases—from prokaryotes to invertebrates, vertebrates, and plants.The so-called C-Value Paradox refers to the finding that genome size does not always rise in proportion to an organism's apparent level of complexity.In comparison to prokaryotes (organisms without a nucleus), such as bacteria, eukaryotes, or species having a nucleus to hold their genetic material (DNA), do have larger genomes. Only 4 million base pairs make up the best friend of microbiologists, E. coli. On the other hand, the fly, Drosophila Melanogaster, has 140 million base pairs. Clearly, a fly is more complicated than a bacterium.

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What is the purpose of latitude and longitude

Answers

Answer:

B) They allow a region's location to be determined exactly.

Explanation:

Both lines were invented by people to identify and locate specific places on earth. Latitude is used to identify particular north-south locations, and longitude is used to identify a particular east-west. The combination of latitude and longitude allows you to define and label any location on Earth accurately.

Describe the hygiene hypothesis and the role that eosinophils play in it. Why does having a parasitic worm help us

Answers

In medicine, the hygiene hypothesis states that early childhood exposure to particular microorganisms (such as the gut flora and helminth parasites) protects against allergic diseases by contributing to the development of the immune system.

What is the role of eosinophils in hygiene hypothesis ?

Eosinophils are multifunctional granulocytes that contribute to initiation and modulation of inflammation.

Eosinophils are extremely versatile effector cells that damage tissues or modulate the activity of other immune and stromal cells.Why does having a parasitic worm help us ?

This is because parasitic worms have evolved strategies to block parts of the human immune system.

These parts of the immune system, namely the eosinophils and IgE antibodies, are also the main players in allergies, IBD, and many other inflammatory diseases

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Which of the samples are composed of matter? sound of a birdsong ice cubes in a glass warmth from a fire air inside a balloon clouds in the sky

Answers

Ice cubes in a glass. The others are mostly figurative things. Matter is a physical object that you can hold.

Ice cubes in a glass  samples are composed of matter. Matter is a physical object that you can hold.

What are the properties of matter ?

Matter is defined as as the physical object with total mass  occupied in space, as all the physical structures are derived from matter, present in three basic states such as solid, liquid, and gaseous states.

The basic unit of matter is called as  atoms that make up the objects which can be visible and sensed, the amount of matter present  in an object can be calculated by its mass.

The physical property of matter is not dependent on its chemical composition such as Density, color, hardness, melting and boiling points, and electrical conductivity are the examples.

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The effect of sympathetic nervous system stimulation on the heart is to: Group of answer choices increase the refractory period. increase the heart rate and decrease myocardial contractility. decrease calcium influx. decrease heart rate and increase the strength of myocardial contraction.

Answers

The effect of sympathetic nervous system stimulation on the heart is to increase heart rate and myocardial contractility.

In the sympathetic nervous system (SNS), as the sympathetic stimulation increases, the heart rate also decreases along with the force of contraction.

The heart rate increases because of the release of hormones catecholamines - epinephrine and norepinephrine whereas the force of contraction increases because of a higher end-systolic volume [ESV] which requires a forceful heart contraction to pump more blood out of the ventricle which will decrease the ESV value.

The end-systolic volume [ESV] is the amount of blood that remains in a ventricle after a contraction (systole) which is to be maintained at around 50 mL of blood.

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The study of biology can be understood through the organizational hierarchy of life. Each level of life builds upon the next level, and this increasing complexity is what leads from molecules up to an entire ecosystem. How is the community level different from the other levels of life

Answers

The community level is different from the other levels of life as a community is made up of all the species that can coexist and possibly interact in one place.

The study of biology can be understood through the organizational hierarchy of life.

Each level of life builds upon the next level, and this increasing complexity is what leads from molecules up to an entire ecosystem.

In biology, the term "community" describes the collection of coexisting, interacting organisms, whether they are of the same species or not.

Members of a community tend to influence each other's abundance, distribution, adaption, and existence as a result of their interactions.

Community function and community structure are two of its key characteristics.

The community function is related to energy flow, community resilience, and community resistance while community structure is related to biotic composition.

Hence, the community level is different from the other levels of life.

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Scientists are hopeful that npy can be used in combination with gnrh to treat certain cases of female infertility. Individuals with a deficiency in what receptor system would be most likely to benefit from such a treatment?.

Answers

According to the research, individuals with a deficiency in GnRH receptor system would be most likely to benefit from such a treatment.

What is GnRH receptor system?

It is follicle-stimulating hormone being the main regulator of reproductive functions, estrogen levels rise during the menstrual cycle until enough estrogen is present to stimulate the release of GnRH and luteinizing hormone.

Progesterone in high concentrations (eg, during the luteal phase of the menstrual cycle or during pregnancy) reduces the response of the pituitary to GnRH.

Therefore, we can conclude that according to the research, individuals with a deficiency in GnRH receptor system would be most likely to benefit from such a treatment.

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In the electrolysis of water, how long will it take to produce 115.0 L of H2 at 1.0 atm and 273 K using an electrolytic cell through which the current is 121.0 mA

Answers

It will take 2273 h.

Here, the ideal gas equation is used.

What is the ideal gas law?

According to the ideal gas law, a gas's pressure is directly proportional to its volume and temperature.

[tex]PV = nRT\\[/tex]

where,

P = Pressure

V = Volume

n = No. of moles

R = Ideal gas constant

T = Temperature

Given,

V = 115.0 L

P = 1 atm

T = 273 K

I = 121 mA

R = 0.0821 atm. L/mol.K

Put the values in the above formula

[tex]n = \frac{PV}{RT}[/tex]                            

  [tex]= \frac{1(115)}{(0.0821) (273)}[/tex]

  [tex]= 5.13 mol[/tex]

The equation says,

2H⁺ + 2e⁻ → H₂

no. of electrons = 2

1 mol of the electron produces a 96500 C charge

5.13 mol of electrons will give = 5.13 × 2 × 96500

                                                  = 990,090 C

I = 121 mA = 0.121 C/s    (1mA = 0.001 C/s)

We know,

q = It

where,

q = charge

I = current

t = time

t = q/I

t = 990,090/ 0.121

t = 8182562 s

t = 2273 h

Therefore, it will take 2273 h.

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Which describes how to correct farsightedness?

Use a convex lens to move the image formed by the eye forward so it hits the retina.
Use a concave lens to move the image formed by the eye forward so it hits the retina.
Use a convex lens to move the image formed by the eye backward so it hits the retina.
Use a concave lens to move the image formed by the eye backward so it hits the retina

Answers

Answer : a is the the answer

Answer:

a

Explanation:

i took the test

What type of chromosomal abnormality can lead to multiple copies of a gene, some of which can incur mutations that can lead to the evolution of a new function?

Answers

A trisomy is a chromosomal condition characterized by an additional chromosome. A person with a trisomy has 47 chromosomes instead of 46.

Trisomy means the presence of an extra chromosome in some or all of the body's cells. This results in a total of three copies of that chromosome instead of the normal two copies. For example, Down syndrome (trisomy 21) is caused by having three copies of chromosome 21 instead of the usual two copies.

This genetic condition is the result of a genetic mutation where your cells don't divide as they should. You can't prevent this abnormality from happening during cell division.

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Calculate the minute ventilation for the 5mm tube and then for the 3 mm tube. What effect does decreasing tube radius have on resistance and minute ventilation?

Answers

Calculating minute ventilation, this formula should be used:

Minute ventilation = tidal volume x respiratory rate (normal is 4-6 L/min) Tidal volume = alveolar space + dead space.

What is minute ventilation?

Minute ventilation is the tidal volume times the respiratory rate, usually, 500 mL × 12 breaths/min = 6000 mL/min.

Therefore, the 5mm tube will be calculated as:

500 x 15= 7,500 mL/min.

And the 3mm tube will be calculated as:

65 x 15= 975mL/min

The effect decreasing the tube radius will have on increased resistance and minute ventilation is that there will be a decrease in the tube minute ventilation.

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What is the primary molecule that makes up cell membranes?

Answers

Answer:

Phospolipids are the primaey molecules that makes up cell membranes.

Other Questions
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