The first phase of the antibody-mediated immune response is the recognition and activation of B cells by antigens.
When the body is exposed to foreign substances called antigens, B cells in the immune system recognize these antigens through their specific receptors. This recognition triggers the activation of B cells, leading to their proliferation and differentiation into plasma cells. Plasma cells are specialized B cells that produce and secrete large amounts of antibodies. Antibodies, also known as immunoglobulins, are proteins that specifically bind to antigens and help in their neutralization and elimination from the body.
Therefore, the first phase of the antibody-mediated immune response involves the recognition and activation of B cells by antigens.
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What type of covalent bond is responsible for holding together the secondary structure of proteins
Answer :Hydrogen Bonds
Explanation:
What are sizes of the fragments from an enzyme digestions (endonuclease) of the Lambda Phage plasmid DNA using Eco RI and Pst I? Make sure to have an uncut and double-cut reaction. Explain the mechanism of action of each enzyme and then list the fragment all sizes and draw the results.
Digestion of lambda DNA with Eco RI generated 6 fragments. The Pst I restriction enzyme produces 29 lambda DNA fragments.
What are restriction enzymes?Restriction enzymes are DNA-cutting enzymes found in bacteria. These are site-specific endonucleases also known as molecular scissors.These recognize and cut DNA only at a particular sequence of nucleotides.DNA from the bacteriophage Lambda (48,502 base pairs in length) is cut with a variety of restriction enzymes and the resulting fragments are separated using gel electrophoresis. Size of fragment of uncut lambda DNA is 48502 b.p.Eco RI recognizes G AATTC
CTTAA G
Lambda phage has 5 recogition sites for Eco RI. It cleaves the DNA at ‘G’ of the above sequence.Relative sites of cleavage in base pairs are 21226, 26104, 31747, 39168, 44972.Sizes of fragments produced when the lambda DNA cut with Eco RI 21226, 7421, 5804, 5643, 4878, 3530.Digestion of lambda DNA with EcoRI generated 6 fragments but 2 of them are so close in size that they are difficult to separate.Pst I recognizes CTGCA G
G ACGTC
The Pst I restriction enzyme produces 29 fragments of lambda DNA. It cleaves the DNA at ‘G’ of the above sequence.The Pst I digest of λ DNA yields the following discrete fragments (in base pairs): 11497, 5077, 4749, 4507, 2838, 2556, 2459, 2443, 2140, 1986, 1700, 1159 1093, 805, 514, 468, 448, 339, 264, 247, 216, 211, 200, 164, 150, 94, 87, 72 and 15.The cohesive ends (12b cos site of bacteriophage) of fragments 11501 bp and 2556 bp may anneal and form an additional band.Learn more about restriction enzymes here:
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Does Pterocaulon Plystachyum affect cell division?
Answer:
polystachyum infusions produced the greatest inhibition of onion root-tip cell division and decreased mitotic index but there was no statistically significant intra or interpopulational variability for the P. polystachyum populations from different sites in regard to their cytotoxic effects.
____________________ evolution states that all life on earth is descended from other life and has transformed from, at times, very different ancestors.
Organic evolution states that all life on the earth is descended from from other life and has transformed from , at times , very different ancestors.
Evolutionary theory is based on ideas of species and related to their gradual decreases.It is given by Darwin which is based on natural selection. Evolution is not theory about the origin of life. Its express about that how species change over time and what many people think there is also little conflict between evolution.
Evolution is the process in which gradual change that takes places over many generation to generations in which species of animals , plants or insects slowly change some of their physical characteristics.
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In the marine mollusk, Aplysia, serotonin binds to a G-protein-coupled receptor and activates a Gs subunit. The resulting activation of PKA leads to phosphorylation and closure of K channels. What effect would this have on the cell
The serotonin binds to a G-protein -coupled receptor and activates a G-subunit . This results in activation of PKA and closing of the potassium channels. This will subsequently decrease the influx of potassium ions into the cell, and lead to depolarization of the cell. This changes the membrane potential of the cell.
Aplysia are sea slugs which fall under the category of mollusks. Serotonin is a hormone which is responsible for the transfer of electrical signals from the brain to different parts. In this particular mollusk, serotonin was studied to find that it is an essential neurotransmitter that is responsible for the maintenance of synaptic plasticity in the neurons. Synaptic plasticity is the feature which is essential for the communication of neurons. This is the modification which occurs at the synapses during the transmission of synapses. Without this activity, the transmission of signals would be impossible.
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When any of your body cells becomes infected with a pathogen, to what protein do the foreign peptides become attached that initiates the immune response
Interferons
Virally infected cells produce and release small proteins called interferons, which play a role in immune protection against viruses.
What are Interferons ?Interferons prevent replication of viruses, by directly interfering with their ability to replicate within an infected cell.
They also act as signalling molecules that allow infected cells to warn nearby cells of a viral presence – this signal makes neighbouring cells increase the numbers of MHC class I molecules upon their surfacesSo that T cells surveying the area can identify and eliminate the viral infection.Learn more about Interferons here:
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what will happen in absence of semilunar valves?
Answer:
The absence of semilunar valves could cause a fetal death or induced abortion.
Explanation:
Severe regurgitation in both great arteries leads to volume overload in both ventricles, which causes fetal hydrops and death.
Hope this helps!
Select the correct answer from each drop-down menu.
Ruth is presenting the feedback model to her class. Help her complete the statements.
A negative feedback mechanism works by
of a system. A
restore the
variations in conditions. This feedback mechanism tries to negate changes to
feedback mechanism supports a change that occurs in the value of a parameter.
A negative feedback mechanism tries to negate changes so as to restore the variations that occurs in the value of a parameter or system.
What is Negative feedback?This is known to be a method that tend to reverses any kind of movement or deviation from the set point and it then keeps the body parameters to its normal range.
Note that A negative feedback mechanism tries to negate changes so as to restore the variations that occurs in the value of a parameter or system.
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The correct sequence for the phases of the human cell cycle, starting with a newly divided cell, is?
Starting with a newly divided cell, the correct sequence for the human cell cycle phases are interphase followed by mitosis and then cytokinesis.
Interphase of the cell cycle does not involve any cell division. It is a period of growth and replication of the nuclear DNA. The cell prepares for the division in this stage. Interphase is further divided into the G1, S and G2 phases. Mitosis is the next phase of the cell cycle which involves the division of the cell in order to form daughter cells. Mitosis is further divided into the prophase, metaphase, anaphase and the telophase. Cytokinesis marks the end of the mitosis and this is where the cell actually separates to produce two daughter cells.
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Two organisms of different species mate and produce offspring that cannot mate with its siblings or with members of either parental species. This is an example of __________.
Two organisms of different species mate and produce offspring that cannot mate with its siblings or with members of either parental species. This is an example of hybrid infertility.
Hybridization is the technique used to combine two distinct hereditary, which might cooperate in a dissonant way. This sort would be supposed frequently prompt to awful outcomes. The combination in a single organic entity of two genomes that are independently useful will mostly bring about adverse interaction on the grounds that every one of the genes in a single genome should be viable with every one of the genes in the other.
Hybrid infertility and sterility, on the whole known as half-breed incongruence, can diminish the exchange of hereditary variations between species. In this way, hybrid infertility can be significant during the process of speciation by acting as a reproductive inhibitor.
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Coalescent theory uses which two values when evaluating diversity of population and attempting to estimate recent history of a population?
Coalescent theory uses Effective population size (Ne) and mutation rate (µ) hen evaluating diversity of population and attempting to estimate recent history of a population.
A genealogy's gene divergence distribution can be modeled using the coalescent. It is frequently used to calculate population genetic characteristics in natural populations, including population size, migration rates, and recombination rates.Every finite set of genes or alleles has a "coalescent point" where all descendants converge to a single ancestor (i.e., they "coalesce") under the conditions of genetic drift alone.To measure population genetic diversity, it is frequently utilized. characteristics including the size of the population, migration patterns, and Rates of recombination in unmanipulated populationsIt was first created by as the "n-coalescent" Kingman (1982). Others call it the "Kingman." "the coalescent," or simply "the coalescent".learn more about Coalescent theory here: https://brainly.com/question/9640986
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he coronary sinus is a modified vein that collects venous blood from all areas of the heart and drains it directly into the left atrium of the heart.
The given statement that the coronary sinus is a modified vein that collects venous blood from all areas of the heart and drains it directly into the left atrium of the heart is true
What is coronary sinus?On the backside of the left atrium, within the left atrioventricular groove, is the coronary sinus, a sizable venous structure. The coronary sinus is responsible for removing venous blood from the bulk of the heart. Between the right atrioventricular orifice, the fossa ovalis, and the inferior vena cava aperture, it enters the right atrium. A thin, semicircular endocardial fold, also known as the Thebesian valve, frequently protects the coronary sinus.
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The motor neuron and all the myofibers it innervates is referred to as a ____________ . every time a motor neuron sends a nerve impulse to a skeletal muscle fiber, the muscle fiber will
The motor neuron and all the myofibers it innervates is referred to as a __motor units__ . every time a motor neuron sends a nerve impulse to a skeletal muscle fiber, the muscle fiber will contract .
What is the motor units?
The motor unit is the association between the motor neuron and a group of fibers from the muscle.
A single muscle is composed of several motor units. The fibers composing each of them are just a little part of the whole muscle mass, meaning this is the part that will contract.
The motor unit is the basic unit from which the CNS controls motion.
How does contraction occur?The central nervous system (CNS) generates an action potential in the presynaptic membrane.
This action potential provokes the neurotransmitter release (acetylcholine, Ach) into the synaptic space.
The neurotransmitter travels through the synaptic space and reaches the postsynaptic membrane, where it binds to its receptors on the skeletal muscle fiber, causing ion channels to open.
Ion interchange between the extracellular space and the cell interior triggers a series of events that end by depolarizing the muscle fiber membrane, and leading to fiber contraction.
The motor neuron and all the myofibers it innervates is referred to as a _motor unit_ . every time a motor neuron sends a nerve impulse to a skeletal muscle fiber, the muscle fiber will contract.
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Which procedure involves excision of the pituitary gland through the sphenoid sinus without disturbing brain tissue?
According to the research, the correct option is transsphenoidal surgery, this procedure implies the excision of the pituitary gland through the sphenoid sinus without disturbing brain tissue.
What is transsphenoidal surgery?It is a treatment for pituitary tumors that uses the endoscope as a source of vision and that allows the doctor to reach the pituitary gland and nearby areas through the sphenoid sinus, preserving nasal anatomy and functionality.
Generally, this technique is indicated for patients with microadenomas as well as macroadenomas and other pathologies in the region that cause symptoms such as vision loss, headaches, or hormone-related problems.
Therefore, we can conclude that the correct option is transsphenoidal surgery, this procedure implies the excision of the pituitary gland through the sphenoid sinus without disturbing brain tissue.
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Which of the following statements is correct with respect to the use of oxidized sulfate by some bacterial groups
All of the above.
What are sulfur oxidizing bacteria?Any of a wide range of microorganisms that can metabolize sulfur and its components and are significant in nature's sulfur cycle are known as sulfur bacteria. Hydrogen sulfide (H2S), sulfur, and thiosulfate are a few of the typical sulfur compounds that are used by these bacteria as a source of energy. Sulfate is the end result of the oxidation of sulfur.
In deep earth deposits, Thiobacillus, which is common in both marine and terrestrial settings, produces sulfuric acid, which dissolves metals in mines but also corrodes concrete and steel. It also oxidizes sulfur, generating sulfates that are helpful to plants.
I understand the question you are looking for is this:
In seawater, sulfate is the most common anion after chloride. Which of the following is correct with respect to the use of sulfate by some bacterial groups?
Oxidized sulfur-containing molecules have redox potentials lower than those of the nitrogen series.Oxidized sulfur molecules such as sulfate and sulfite serve as electron acceptors.Sulfate and sulfite can receive electrons from hydrocarbons.Sulfate-reducing archaea and bacteria are widespread in the ocean.All of the above.Learn more about sulfur bacteria here:
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A family took their newborn to the doctor. They were worried something was wrong because the baby seemed to be in constant pain. After medical tests revealed the baby had large amounts of lactic acid accumulating in his muscle cells, doctors diagnosed the child with a rare disease in which mitochondria are missing from skeletal muscle cells. How might the lack of mitochondria explain the large amounts of lactic acid in the baby's muscle cells
Mitochondria help in the complete metabolism of sugar to produce energy in the cell (ATP). Mitochondria is the powerhouse of the cell.
Glycolysis is the first step in the metabolism of glucose. By the process of glycolysis, glucose is converted to pyruvate with the generation of ATP and NADH. The pyruvate is then converted to acetyl CoA by the pyruvate dehydrogenase complex which then enters the TCA cycle. The NADH FADH2 generated by Glycolysis and TCA cycle donate their electrons to the electron transport chain which in turn helps in the generation of ATP. Both the TCA cycle and the Electron transport chain take place within the mitochondria. In the absence of mitochondria, NAD+ and FAD are regenerated by fermentation.
In the process of converting 3-carbon pyruvate to 3-carbon lactic acid (C3H6O3), lactic acid fermentation also regenerates NAD+, which enables glycolysis to continue producing ATP in the absence of mitochondria. This leads to the accumulation of lactic acid in muscle cells.
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Animals that lie in cold climates tend to have higher proportions of __________ fatty acid residues in their lipids than do animals that live in warm climates.
Answer: polyunsaturated fatty acid residues
Explanation: Unsaturated fatty acids have a lower melting point so arctic animals have these fatty acids in their membranes.
The bacteria, Angelinus ballerinea secretes a compound that inhibits the growth of other Gram-positive bacteria. Scientists take this compound and add chemical groups to it to make it more stable for use in humans to treat bacterial infections. This is an example of a(n)
The bacteria, Angelinus ballerinea secretes a compound that inhibits the growth of other Gram-positive bacteria. Scientists take this compound and add chemical groups to it to make it more stable for use in humans to treat bacterial infections. This is an example of antibiotic.
What is antibiotic?Antibiotics from the key class of glycopeptides can stop this process. Through five H-bonds, these antibiotics bind to the C-terminal d-Ala-d-Ala of the murein precursor, lipid II, and immature peptidoglycan, preventing transglycosylation and/or transpeptidation during the production of the cell wall.Contrarily, antibiotics have easier access to the thick, porous peptidoglycan layer in the cell walls of Gram-positive bacteria, allowing them to more easily enter the cell and/or interact with the peptidoglycan itself.The two main antibiotics that prevent the synthesis of bacterial cell walls are penicillins and cephalosporins.Penicillin is one of many antibiotics that assault the bacterial cell wall in order to operate. The medications specifically stop the bacteria from producing peptidoglycan, a chemical that gives the cell wall the toughness it needs to live in the human body.
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Misha often experiences severe swelling and joint pain in her fingers and wrists each morning. this pattern of symptoms is most likely due to:______
Misha often experiences severe swelling and joint pain in her fingers and wrists each morning. This pattern of symptoms is most likely due to Rheumatoid arthritis (RA).
Rheumatoid arthritis is an autoimmune disorder and inflammatory condition in which your immune system unintentionally assaults healthy cells in your body, leading to painful swelling(inflammation) in the areas of your body affected. It primarily targets joints, typically several joints at once. Hand, fingers, wrist, and knee joints are frequently impacted. Joint tissue is harmed in a Rheumatoid arthritis-affected joint because of the inflammation of the joint lining resulting in Long-lasting or persistent pain.
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What similarities are there between the ways archaea and bacteria react to difficult environmental conditions?
Archaea and bacteria both have flagella, thread-like structures that allows organisms to help them move forward through their environment.
Three broad branches into which life on earth is divided, those are Eukarya, Archaea and Bacteria. Archaea and bacteria were considered as the part of same taxonomic kingdom as both were considered prokaryotic organisms with no nucleus.
Through research scientist discovered that archaea has prominent molecular differences from bacteria. Genetic inspection also revealed that Archaea and Eukarya have a closer phylogenetic relationship to one another than to Bacteria.
Archaea and Bacteria both being prokaryotes , they don't have a nucleus and lack membrane-bound organelles. They are tiny and single-cell organisms and they exist as rods, cones, plates and coil.
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Increasing the strength of the stimulus applied to the sensory receptor increased _______
What can be known about Mendel's five-part hypothesis?
Answer: It is an answer to a scientific question and is based mostly on his research.
Explanation:
Why is it important to homeostatically regulate csf composition independently of the blood?
It is very important to regulate homeostatically Cerebrospinal fluid composition because neurons are not like other cells they requires a unique environment to sustain its function properly. This homeostatic regulation also protects neurons from blood-borne proteins, cells and toxic factors.
Cerebrospinal fluid (CSF) is found in the subarachnoid space that surrounds the brain and spine and ventricles (Shaft-like spaces inside of the brain). The purpose of CSF is to provide nutrients, remove waste, and cushion the brain and spine. It is also important to drain CSF properly as pressure like hydrocephalus results from the gradual blockage of the CSF-draining pathways in the brain, that results in blockage of ventricles thus compressing the brain within and eventually damaging or destroying the brain tissue.
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When the ground position of a front moves so that warm air occupies territory that was previously held by cold air, what type of front is it?
When the ground position of a front moves so that warm air occupies territory that was previously held by cold air, It is knows a warm front.
The area where a warm air mass is replacing a cold air mass is known as a warm front. The air behind a warm front is warmer and more humid than the air in front of it. Warm fronts typically migrate from the southwest to the northeast.A warm front is a density discontinuity that is usually seen on the margin of an isotherm gradient that faces the equator and is situated at the leading edge of a homogenous warm air mass. Since warm air is thicker and more difficult to remove from the surface of the Earth than cold air, warm fronts move more slowly than the cold fronts that typically follow them.
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You are part of a research group experimenting with signaling molecules that would tell cancer cells to stop dividing. The cancer cells have inactive receptors on their plasma membrane so you need an alternate method of getting the signals into the cells. What could you use
Gap junctions for direct contact is used to cancer cells have inactive receptors on their plasma membrane so you need an alternate method of getting the signals into the cells.
What about cancer cell?The MAP kinase route, which controls cell proliferation, and the phosphoinositide 3-kinase (PI3K) pathwayIt controls cell metabolism and survival, are the two RAS signaling pathways that are most frequently linked to cancer.Signaling pathways are affected by cancer-causing mutations. The genomic changes in cancer cells can be linked to signaling pathways that regulate tumor-related functions and put in the perspective of distorted larger signaling networks that promote cancer progression.To transmit signals from the extracellular environment to the cell nucleus, where they activate particular genes necessary for cell division, growth, and differentiation.Learn more about gap junction here:
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Comparisons of tooth wear in living apes and extinct Miocene apes suggest that some extinct species of apes ate Group of answer choices leaves, grass, and bark. nuts, fruits, and small animals. leaves, nuts, and fruits. insects, fruit, and leaves.
Comparisons of tooth wear in living apes and extinct Miocene apes suggest that some extinct species of apes ate a Group of leaves, nuts, and fruits.
THE MIOCENE APESAs many as 30 species of apes lived in large areas of Africa, Asia, and Europe during the Miocene, when they underwent their largest radiation.
What led to the reduction in the number of ape species?The diversity of ape species decreased during the Late Miocene as a result of climate changes that increased seasonality (and progressively replaced many forests with grasslands) and competition with an ever-increasing variety of monkey species.
Extinct species of apes ate:-Its teeth suggest that this species, which lived in forests, consumed fruits, seeds, leaves, and other types of plants. It most likely consumed some bamboo as well. About 100,000 years ago, the ice age began, and it drastically altered the landscape and the amount of tree cover. The G blacki needs a tremendous amount of food due to its size.
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What is the difference between running a sam spade investigation versus searching dns records?
In the case of DNS record; You launch windows command by navigating to start. -Type NSLOOKUP and then press enter. -Afterwards you enter the name you wish to query. On the other hand, Sam space is mainly run on the network and it can be used by network administrators to track down intruders and hackers.
Sam Spade for Windows offers a suite of tools for protecting against spam on mail servers, analyzing and troubleshooting web servers, and gathering information on Internet hosts.
DNS records (aka zone files) are instructions that live in authoritative DNS servers and provide information about a domain including what IP address is associated with that domain and how to handle requests for that domain.
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Hunter syndrome is a rare genetic disorder in which large sugar molecules called glycosaminoglycans build up in body tissues. Hunter syndrome causes abnormalities in many organs, including the skeleton, heart, and respiratory system. In severe cases, this leads to death during the teenage years. Hunter syndrome is caused by a recessive gene on the X chromosome. If a woman who is normal (but had a father with the disease) marries a normal man, what are the chances of having a daughter affected by the disease
Answer:
Hunter syndrome is a very rare, inherited genetic disorder caused by a missing or malfunctioning enzyme. In Hunter syndrome, the body doesn't have enough of the enzyme iduronate 2-sulfatase.
What is the most likely effect of a mutation that changes the repeat sequence found in terc from 3’-cccaau-5’ to 3’-ucaggacg-5’?.
If the repeat sequence of telomere changes from 3’-cccaau-5’ to 3’-ucaggacg-5’ due to any mutation then the telomerase enzyme will be unable to attach to the 3' overhung of the telomere sequence and cannot elongate new DNA strand [telomeric part] as a result, the telomeres of chromosome cannot be elongated and the entire chromosome or the cell will be lost after few rounds of division.
Mutation: This can be described as a random change in the nucleotide sequence due to which the protein sequences change hindering the function performed by the particular protein.
Telomere: They are short repeating sequences found at the end of the chromosome whose function is to save the chromosomes from degradation.
But after each round of replication, the length of the telomeres becomes shorter than the previous and after a certain number of cell divisions, the telomeres become so short that they trigger the cell to stop dividing or to self-destruct (undergo apoptosis).
So, to prevent the shortening of telomeres, the TERC gene codes a telomerase enzyme which is a type of reverse transcriptase. After every cell division, the telomerase enzyme gets attached to the 3' end of the shortened telomere end and synthesizes the complementary DNA to the RNA part of the enzyme until the length of the telomere is restored again.
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The most common reportable disease in the united states is:_______
a. cystitis.
b. lymphogranuloma venereum.
c. gonorrhea.
d. syphilis.
e. candidiasis.
Gonorrhea is a sex-transmitted disease caused by a bacteria that equally infects men and women. Option C.The most common reportable disease in the United States is gonorrhea.
What is gonorrhea?Gonorrhea is transmitted by sexual contact. The disease equally affects men and women, who may or may not experience symptoms. This is a very common affection that affects mostly people between 15 and 25 years old.
More than a million cases of Gonorrhea per year are reported in the United States. Because of the high incidence of the disease, especially in young people, health workers must inform the State Board of Health about all Gonorrhea cases.
The correct option is C. The most common reportable disease in the united states is:_gonorrhea_
Due to technical problems, you will find a more detailed explanation in the attached files.
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